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Rhodiola: Root Yourself for Back to School and Work!

Posted September 14, 2017

By: Dr. Colin O’Brien ND, Ontario Regional Manager, Cyto-Matrix

Summer has once again come and gone and it’s time to get back into a solid routine. Whether you’re a parent with toddlers headed back to school, a graduate student or just an everyday worker going back into the office after some vacation time, we all could use a little extra support to help us push through the busy fall season. Regular sleep, a healthy diet and moderate exercise will always be the foundation for stress resiliency, but when more support is needed, a little-known herb called Rhodiola rosea can help your body adapt and adjust accordingly.

What is Rhodiola?

Rhodiola rosea, also known as ‘golden root’, is a medicinal herb that has traditionally been used in Russia, Scandinavia and other European countries for a wide variety of health concerns. It is considered an adaptogenic herb, meaning that it can help your body adapt to stress! As you can imagine, the ability to increase resiliency to stress is highly sought after by many parents, students, workers and others in high pace lifestyles, so the popularity of rhodiola has been growing steadily in North America.


Why Should You Consider Using Rhodiola?

Traditionally, rhodiola has been used as a stimulant, to increase attention span, memory and physical endurance, but also to treat a wide variety of health concerns such as anxiety, depression, fatigue, anemia, infections and impotence. Most importantly, rhodiola is particularly effective for these concerns when stress is at the root cause of the problem.

Clinical research has been able to confirm many of these wonderful applications for rhodiola root extract. Here are a few highlights:

Burnout: Although rhodiola has been traditionally used for this purpose for many years, brand new research has supported its ability to help people suffering from symptoms of burnout. 118 men and women between the ages of 30-60 took rhodiola rosea extract for 12 weeks and significant improvements were noted in areas of emotional exhaustion, fatigue and joy. An increased ‘zest of life’ and sexual interest and functioning were also found in those taking rhodiola root.

Exercise Performance & Recovery: Research has shown that even short term dosing (ie 4 days) of rhodiola can increase time to exhaustion and oxygen utilization during athletic performance. Perhaps just as important, rhodiola has been found to reduce levels of inflammation in the body 5 hours post-exercise and also 5 days after intense exercise, meaning that it can speed recovery times.

Depression & Anxiety: In a 2007 study of 60 patients suffering from mild to moderate depression, rhodiola extract was shown to significantly improve depression markers such as insomnia, self-esteem and emotional stability when compared to placebo. Similar improvements have been noted in studies and in practitioner feedback when examining the benefits on generalized anxiety disorder. Clinically, many practitioners recommend rhodiola to patients that present as “wired and tired”, meaning anxious and on edge, yet exhausted.

How Does Rhodiola Work in the Body?

Research has found that one of the ways in which rhodiola positively impacts the mental health of an individual is through the balancing of neurotransmitters, chemicals in the brain that are responsible for regulating mood. Rhodiola specifically prevents the breakdown of adrenaline, serotonin, dopamine and acetylcholine, thereby increasing their action in the brain. This ultimately improves cognitive measures such as mood, memory and attention.

Although there are many active ingredients within the whole plant extract, rosavins appear to hold most of the medicinal power. With this in mind, it is important to select a rhodiola supplement that specifies the rosavin content.


But is Rhodiola Safe?

            Yes, rhodiola is extremely safe for the vast majority of the population. However, pregnant women, nursing mothers and those diagnosed with bipolar disorder should avoid or consult with a qualified healthcare practitioner before beginning supplementation.

In the end, rhodiola root is a great option for those feeling stressed or overwhelmed. Whether high stress in your life leads to poor sleep, depressed mood, low energy or even recurring colds and flus, rhodiola may be that missing piece to help get you out of your slump. Everyone needs support from time to time and rhodiola can be the much-needed crutch during a busy transition!


Select References:

  1.  Hung SK, Perry R, Ernst E. The effectiveness and efficacy of Rhodiola rosea L.: A systematic review of randomized clinical trials. Phytomedicine 18 (2011) 235–244.
  2. Bystritsky A, Kerwin L, Feusner JD. A pilot study of Rhodiola rosea (Rhodax) for generalized anxiety disorder (GAD). J Altern Complement Med. 2008 Mar;14(2):175-80.
  3. Kasper S and Dienel A. Multicenter, open-label, exploratory clinical trial with Rhodiola roseaextract in patients suffering from burnout symptoms. Neuropsychiatr Dis Treat. 2017; 13: 889–898.
  4. De Bock, K., Eijnde, B.O., Ramaekers, M., et al., 2004. Acute Rhodiola rosea intake  an improve endurance exercise performance. International Journal of Sport Nutrition & Exercise Metabolism 14 (3), 298–307.
  5. Abidov, M., Grachev, S., Seifulla, R.D., et al., 2004. Extract of Rhodiola rosea radixof Experimental Biology and Medicine 138 (1), 63–64. reduces the level of C-reactive protein and creatinine kinase in the blood. Bulletin of Experimental Biology and Medicine 138 (1), 63–64.
  6. Darbinyan, V., Aslanyan, G., Amroyan, E., et al., 2007. Clinical trial of Rhodiola rosea L .extract SHR-5 in the treatment of mild to moderate depression. Nordic Journalof Psychiatry 61 (6), 503.

Clinical Feedback from 2 years of Bio-Ferra prescribing

Posted November 15, 2016

By: Dr. Andrew Krause ND CSCS CISSN, Ontario Regional Manager, Cyto-Matrix

One of my favourite parts of my role with Cyto-Matrix is how often I get to see colleagues at their clinics, and hear about their clinical successes in practice. One product that has been getting particular mention in meetings over the past few months is Bio-Ferra.

Bio-Ferra is a liquid iron that uses a form of iron called Polyaccharide Iron Complex (PIC). We chose to use this form of iron in Bio-Ferra for three reasons:
1. PIC is a non-ionic form of iron, which means it does not need high stomach acid to be absorbed. This runs contrary to many other forms of iron that are prominent on the market, since an ionic form of iron requires high stomach acid to break the bond between the iron and whatever agent has been bound to it. Common agents bound to iron are: gluconate, fumarate, succinate, and bisglycinate. (1)
2. PIC is also significantly less constipating than other forms of iron, and therefore encourages better compliance than with other forms of iron (Bio-Ferra also has a palatable green apple taste). PIC has a higher lethal dose (LD50) than any other form of iron on the market (2,3), which makes it safe, along with being tolerable.
a. Bio-Ferra has been on the market for 26 months as of this writing, and we have yet to have a patient call in and complain about constipation related to the product!
3. PIC is a vegan source of iron! At Cyto-Matrix, we are always mindful of ensuring that our products can be used by the largest proportion of patients possible, so this was an important feature when choosing PIC.


Now that you understand the “why” behind Bio-Ferra, here are some of the clinical results we’ve seen and heard from clinicians using Bio-Ferra in practice over the last 2 years.
1. A pregnant patient was able to double her ferritin (16 to 32mcg/L) in two weeks with 2 teaspoons of Bio-Ferra per day, even considering her 1L of blood loss during the birthing process.
2. One clinician has had 4 cases in the past year where giving 2 tsps per day of Bio-Ferra doubles the patient’s ferritin levels in 3-6 months.
3. Another pregnant patient was able to raise her ferritin from 16 to 52 mcg/L with 3tsp per day dosing in 6 weeks, having also lost blood during the birthing process.
Among the many other iron products on the Canadian natural health product market, Bio-Ferra is a safe option that limits constipation, and is clinically effective at improving the symptoms of iron deficiency.
1. Ma et al. Effects of Different Doses and Duration of Iron Supplementation on Curing Iron Deficiency Anemia: an Experimental Study. Biol Trace Elem Res (2014) 162:242–251
2. Oral Iron for Anemia: A Review of the Clinical Effectiveness, Cost-effectiveness and Guidelines. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2016 Jan.
3. Klein-Schwartz, Wendy. Toxicity of Polysaccharide–Iron Complex Exposures Reported to Poison Control Centers. Ann Pharmacother 2000; 34:165-9.

Clear Skin Matters: Your Guide for Treating Acne

Posted April 21, 2016

Written by: Emily Elliot
Edited by: Ali Cockerill

Many patients concerned with acne arrive at the naturopathic doctor perplexed and frustrated as they express, ‘I have tried everything and nothing works!’ While the number of ‘acne fighting’ products that line the shelves of drug stores and supermarkets are constantly growing and promises of clear skin are endless, the treatment of acne is complex and the exact science has not yet been discovered. While the exact pathogenesis of acne is still largely a topic of scientific investigation, the good news is that many lifestyle changes have well documented results. Additionally, acknowledging that as patients that their hormonal status is unique may be a starting place for answers. While expensive lotions and creams are an excellent addition to a proper skin care regiment, acne is truly a journey from the inside out. Our skin is a very important messenger that can offer us insight into what is happening internally. Let’s review some of the strategies that are effective for clearing up the skin.

Mastering your meals, the best diet for acne:
The debate on whether or not diet contributes to acne is longstanding. However, studies are finally identifying what dermatologists have always truly known – yes, there is definitely a link between diet and breakouts. It is no coincidence that some non- Westernized populations report almost zero occurrence of acne lesions! (1)
Specifically, studies have shown reduced acne lesions and the associated improvements in insulin sensitivity with the consumption of a lower glycemic diet (RCI) (1). A diet in higher glycemic foods will ultimately spike blood sugars leading to increased androgens and IGF-1, which increases secretion of oil and clogs pores.

A low glycemic diet for acne should include lots of healthy fats (olive oil, fatty fish, nuts and seeds), plenty of fibre (25 g for women and 38 g for men), lots of dark leafy greens and an appropriate protein calculation for one’s body weight (a minimum of 0.8g/Kg of body weight). The anti-acne diet should also minimize dairy products as they have also been linked to increased IGF-1 production.

Focusing on lymph is no waste:
Exercise recommendations for the patient with acne can be met with some resistance. Fears may emerge regarding how ‘sweat build up’ may detriment the skin. However, it is important to focus on the benefits that come from regular exercise and to promote proper hygiene practices before and after workouts. Many patients working with acne have issues detoxifying and may display signs of a sluggish lymphatic system like: allergies, itching, chronic fatigue etc. Recommendations like cycling, running, walking, yoga and ‘rebounding’ (trampoline jumping) have all been documented for their lymphatic benefits (2). Through daily movement and generating lymphatic flow, the body brings forth oxygen and nutrients to the skin’s surface as it works to eliminate cellular debris and waste products that can build up in acne (3). There really is no substitute for a healthy, active lifestyle. Explaining the mechanics of lymphatic detox may empower the patient to see how movement can positively promote their anti-acne efforts.

Tame hormonal havoc:
Once diet and lifestyle have been approached, hormonal status is a vital part of the acne investigation. Hormonal acne is often linked to the menstrual cycle and can appear around the region of the chin, hairline and back. High androgens (testosterone and its breakdown product dihydrotestosterone) are frequently cited as a hormonal cause of acne (voice changes, hair loss on the head, irregular menstrual cycles in women, weight gain etc.)(4). However, it is important to rule out other hormonal presentations that could use balancing. For example, are there signs of high progesterone (depression, weight gain and increased fat storage, poor blood sugar balance) or low progesterone (hair loss, anxiety, increased allergies, sluggish metabolism etc.) (4). Testosterone, estrogen and progesterone all keep each other in fine balance, so don’t forget to assess all three of these important hormones. (Note: high cortisol can be implicated in testosterone production as well, a quick check on cortisol status may be well indicated too).

Skin superstars: In general, improving skin vitality and health relies on a few key players. Typical recommendations are Vitamin A 25000-50000 IU (contraindicated in pregnancy), Vitamin C 1000-5000 mg and Zinc 15-25 mg, making Cyto-Matrix’s ‘ACEs and Zinc’ truly a ‘skin basic’ (5). Reduced levels of serum zinc have also been identified in patients with increased acne lesions making it an excellent addition to the anti-acne treatment plan (1).

Essential fatty acids are also crucial in maintaining that healthy skin glow we all long for. EFAs found in Cyto-Matrix’s Omega D3 liquid forte not only hydrate the skin and replenish the skin’s barrier but also offer anti-inflammatory properties that are highly beneficial in an inflamed condition like acne. An important focus in skincare is not just combating the condition but also promoting the formation of healthy skin in general.

Boosting bowel terrain:
Oral probiotics help to reduce systemic inflammation and oxidative stress that are characteristic of acne as well as modulate IGF-1, one of the primary proteins linked to acne proliferation. The benefits of supplementation have also been documented for patients who are taking antibiotic treatment and suffering from the side effects of these treatments. One study showed the synergistic benefit of taking probiotics with minocycline when compared to the antibiotic alone as the combination group showed the greatest reduction in acne lesions when compared to the other controls (6).

Mindful medicine for acne:
The emotional effects of acne can be intense and extensive. One important study revealed that even in patients with mild acne, there were feelings of low self-esteem, depression and suicidal thoughts (7). Checking in on one’s overall journey with acne and validating their frustration is a crucial part of patient care and may hold one of the final pieces of the puzzle. When mind, body and soul are all honored as part of the patient’s journey, the truest healing begins.

(1) Logan, C and Treloar, V. The Clear Skin Diet. Naperville, IL. Cumberland House Publishing.
(2) Exercise for the Lymphatic System. (2016). Retrieved from
(3) The Lymphatic System. (2013). Retrieved from
(4) Turner, N. The Hormone diet. USA. Random House.
(5) Natural Ways to Treat and Prevent Acne. (October 2012). Retrieved from
(6) Kober, M and Bowe, W. (2014). The Effect of Probiotic on Immune Regulation, Acne and Photoaging: International Journal of Women’s Dermatology , 1 (85-89).
(7) Dunn, L. (2011). Acne in Adolescents: Quality of life, self-esteem, mood and psychological disorders: Dermatology Online Journal, 17 (1): 1.

Coffee Lovers Listen Up! A novel and delicious way to boost protein in the morning

Posted March 3, 2016

We want to let you in on a little secret. Are you a lover of coffee? A health-nut? Always on the hunt for easy breakfast solutions that make crawling out of bed just a little easier? Here’s our favourite coffee drink… ever. Give it a go and shake up your morning.

Coffee blend

Provitalex powdered creamy latte:

  • 2 tbsp coconut oil
  • 1 scoop of Cyto-Matrix Provitalex® Protein Powder
  • ½ (ish) cup of coffee (decaf or regular)

Blend up and serve immediately.

This creamy delight will have you boosted up on blood sugar stabilizing protein and hunger satiating fats as well as offer a delicious coffee treat that’s not laden with artificial syrups or other unhealthy fillers. Can it get any better than this? We’re not sure.

Who knew you could merge your morning protein shake and coffee into one? So go ahead and hit snooze, your morning routine just got a little easier.

Written by: Emily Elliot
Credit to Ashley Margeson who is the founder of the Cyto-Matrix version of this drink. Connect with Ashley at


8 Ways to Master Stress as a Naturopathic Student

Posted May 22, 2015

By Emily Elliot
Student Representative, Canadian College of Naturopathic Medicine

You have heard it all before, everything in balance. In fact, as a student of naturopathic medicine you preach it to friends and family. Yin cannot steal too much from yang or it depletes. Light must draw from dark to expand. Soy can have positive estrogen modulating effects, only in certain amounts. Get your cardio, but don’t take too much impact on your knees. Although we teach balance as one of the primary pillars of Naturopathic Medicine, it sometimes feel like an extraordinary task. After writing over 113 exams at CCNM and finishing over 107 assignments, here are my tips for managing stress as a naturopathic student.

1. Create space

Take time at the start of every semester, every week and every day to lay out your priorities. Waking up each day with priorities in mind will make sure that they never slip through the ‘to do list’. By taking the time to indulge in those things that ignite you and those people that love you, you can better attack your school work – more focused, more inspired, more efficient. If everything seems to be just a little too much, sometimes we just need to change our perspective. Where is your place of perspective – the park, the climbing gym, on the open trails? Change your vantage point daily and watch how your perspective changes too.

2. Call a friend

In days past, we were more connected. Ironically, as we have become more ‘plugged in’ in a vast sense, we’ve lost touch with our small, local communities. Not only can studying in a small group speed along studying, it offers us a sense of belonging. (Believe it or not, someone else was courageous enough to sign up for 18 exams a semester too.)

3. Let loose in your studying

Did you know that lots of musical bands have a creative process that they use to write and memorize music? They will throw jars of magenta, turquoise and yellow onto a white wall in order to ‘see their music’. Studying is also an art. Let your logistical side escape you and let loose in your studying. Take turns acting out homeopathic traits (you won’t believe how well this works!) Record yourself speaking in Chinese and play it back to yourself. Turn your physical medicine assessments into a dance, (who knew that ‘speeds test’ is the second move in the macarena?) Studying isn’t a sentence, it’s a word.

4. Reinvent the wheel

They say not to reinvent the wheel, but why not? A demanding program shouldn’t squash us but rather, it should call on our creativity. Were you in the routine of trekking 45 minutes to the gym and 45 minutes back? Did Professor. Surprise just announce that next week’s final is actually cumulative? Try youtubing ‘shoulder workouts’ or ‘squats in 5 minutes’. You will be amazed at how sore you can feel after a youtube workout. Don’t mistake quantity of workout for quality. Not motivated to do workouts at home? Post a challenge above your desk and encourage yourself to study for 45 minutes and then move for 15 minutes every hour for four hours. Reward yourself for your discipline. (One more episode of Game of Thrones?)

5. Power up

Isn’t it ironic that just as we need the most energy and nourishment we decide that we don’t have time to plan it, make it or eat it? Try cooking in batches and freezing nutrient-dense soups and stews. Ensure adequate protein by adding a scoop of Cyto-Matrix’s Provitalex Pure Whey into your morning smoothies. As exams come around and we start to give into Tim Horton’s herb and garlic bagels, our protein intake can be the first thing to go. A daily dose of Provitalex will ensure at least 22g of protein daily. Last but not least, pack small snacks to stabilize blood sugar. Almonds, carrots, hummus and apples are some easy go-tos.

6. Don’t sacrifice sleep

At the time it makes so much sense, if you don’t go to bed you have 8 more hours to get through 2 more lectures. You should definitely not go to sleep! Then the night progresses, ‘avena sativa’ sounds like a spell from Harry Potter, you have checked your Instagram 22 times and you know you’ve read the same slide over and over, but it is just not sinking in. Tried, tested and true, it is almost guaranteed that you will learn faster and smarter by sleeping, for at least a while. Give those brain waves a chance on exam day and catch some ZZZs. While zero sleep during exams is not the way to go, a little less sleep is inevitable. Try Cyto-Matrix’s Rhodiola for periods of stress and increased exertion. Not only will it improve concentration and focus but it will improve your overall energy and exam stamina

7. Get in the zone

Naturopathic medicine attracts a lot of type A personalities. Naturally, a type A personality desires to know everything there is to know about every single topic. Not only will this detriment how much you really know, it can also lead to burn out and a loss of passion in the field. Early in the game, take time to map out what you love the most. What is that topic you actively seek out and read up on? Is it hormones? Physical medicine? Adjunctive cancer care? Attracting patients into your future practice will depend on your passion and knowledge, your ability to become a sought after expert. Why not start early? Pay particular attention to what special topic feels like the easiest to learn and start honing your knowledge and skills.

8. Above all, faith

You have confirmed with all of your friends, parents friends, people at the dog park etc. that you are in fact, not going to school to become a homeopath. You have spent time in the shower perfecting your explanation of what it means to be a Naturopathic Doctor. You have silently celebrated when your grandma says, “I can’t believe it, you were right about the gout in my right toe.” Let’s face it, it is a lot of work to defend your profession. Although it is hard work, remind yourself that you have handpicked one of the greatest professions on the planet. You will change people’s lives, shape the future of healthcare and feel the honor that comes with hearing someone say ‘I feel well’. Faith is what called you here and faith is what will carry you forward into a future of fulfillment and abundance. Keep chugging along, the greatest days in your career have yet to come.

Welcome to our new and improved website!

Posted May 3, 2015

By Loretta Masaro, BSc, MBA
CEO, Cyto-Matrix

On behalf of the Cyto-Matrix management team, we are very excited to launch our new and improved website! Our goal is to meet the needs of our customers and we truly hope the new website will mirror the feedback we have received from many of you. We aimed for a site that is easy to navigate, informative yet not overwhelming and cluttered, and one that is accessible whether you are on your home computer, tablet or phone screen. The addition of the blog components will allow management and scientific staff to post just-in-time information on the latest news and/or clinical applications in natural health care.

Cyto-Matrix was founded 12 years ago with a mission to becoming the most trusted professional natural health products brand in Canada.  To date, we have thousands of naturopathic doctors, medical doctors and specialty pharmacies across every province in Canada loyally prescribing our brand to even their most sensitive patients. Cyto-Matrix is one of the most respected professional brands in both of the Canadian accredited naturopathic colleges (BINM, CCNM). We value all the feedback we receive from our doctors and strive to deliver products which meet the needs of their patients in terms of efficacy, safety and delivery formats.  This feedback combined with best available evidence and strict adherence to Health Canada’s Natural and Non-Prescription Products Directorate’s guidelines enables us to design products that Canadians can trust for positive health outcomes.

We thank you for your loyalty to our brand and for continuing to provide feedback to help us improve year after year.